Anolis sagrei, also known as the brown anole, is native to Cuba and the Bahamas. It has also spread to parts of the Caribbean and Central America, including the Cayman Islands.

The brown anole typically inhabits subtropical and tropical environments, characterized by warm temperatures and moderate to high humidity. These regions experience seasonal rainfall, with a distinct wet and dry season.

Brown anoles are predominantly found in lowland areas, often around human habitats such as gardens, yards, and urban areas, as well as natural environments like forests, grasslands, and coastal regions. They are highly adaptable, often living in proximity to water sources and in areas with ample vegetation to provide cover and hunting grounds for insects, their primary food source.