Coluber constrictor, commonly known as the Eastern Racer, is native to North America. Its geographical distribution extends across the eastern and central United States, parts of southern Canada, and northern Mexico. This includes regions from southern Maine through Florida, west to Texas and North Dakota.

Eastern Racers inhabit a variety of environments, primarily preferring open or semi-open areas. These include fields, grasslands, open woodlands, scrublands, and along the edges of forests. They tend to avoid dense forests and overly arid regions.

As a diurnal snake, the Eastern Racer is active during the day and plays a vital role in controlling rodent and insect populations. Its ecological niche includes occupying a diverse range of habitats where it can find ample prey such as insects, small rodents, frogs, and other reptiles. The species exhibits regional adaptations, including variations in size and coloration, to better blend into local environments.