Thelotornis usambaricus, commonly known as the Usambara vine snake, is slender with a cryptic brown and green coloration. It inhabits the forests of East Africa, primarily in Tanzania's Usambara Mountains. It is arboreal, diurnal, and known for its exceptional camouflage among vines and branches.

Thelotornis usambaricus, commonly known as the Usambara vine snake, is native to the Eastern Arc Mountains of Tanzania, specifically the Usambara Mountains and surrounding areas in East Africa. This region is part of a biodiversity hotspot known for its high levels of endemism.

The Usambara vine snake inhabits montane and sub-montane forests within the Eastern Arc Mountains. These areas are characterized by a humid, tropical climate with significant rainfall, which supports dense forest vegetation.

The Usambara vine snake is an arboreal species that primarily resides in the canopy and understory of forested areas. Its slender body and cryptic coloration allow it to blend seamlessly with vines and branches, aiding in its hunting strategy for capturing prey such as lizards and birds. This snake plays a role as both predator and prey within its ecosystem, contributing to the ecological balance of the forest habitat.